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Michelle L Krishnan, Executive Director, MD PhD

A personal journey full circle, from curiosity about life on Earth to transformative therapies at Novartis

When I was young, my interest in science initially started with the natural world and with animals. There's a BBC Nature presenter and biologist called David Attenborough who's very famous in the UK and he was a really big idol of mine.

Dr Bülent Kızıltan, Global Head of AI & Computational Sciences

From black holes to AI driven drug discovery – collaboration wins the day

What would you say if I told you that 1 + 1 = >2? It may sound extraordinary, but it is an accurate reflection of the work I am currently doing in the field of drug discovery with my team of AI experts at Novartis.

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Ever heard of organoids? The scientists I collaborate with use them all the time. They are simplified and miniaturized tissue-engineered models that mimic the structure and function of real human hearts, brains, kidneys etc. Basically, a super-tiny organ that you grow in the lab. Amazing, right?

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Interview for B.Pharm, MSc in Life Sciences as Clinical Research Cordinator at SCTIMST

Interview for B.Pharm, MSc in Life Sciences as Clinical Research Cordinator at SCTIMST

Sree Chitra Tirunal Institute for Medical  Sciences and Technology (SCTIMST) is an Institution of National Importance under the Department of  Science and Technology, Govt. of India. The joint culture of medicine and technology pioneered by its founders more than three decades ago, has come of age and gained unprecedented acceptance in India. The institute has the status of a university and offers excellent research and training facilities.  

Post : Clinical Research Cordinator - (Temporary)

For Private Funded Project entitled “A multicentre, international randomized, placebo controlled, double-blind, parallel group and event driven Phase 3 study of the oral FXIa inhibitor asundexian (BAY 2433334) for the prevention of ischemic stroke in male and female participants aged 18 years and older after an acute non- cardioembolic ischemic stroke or high-risk TLA "(P-5489)

Qualification & Experience (Essential) : 1. Bachelor degree in Nursing (or) Pharmacy OR Master degree in Life Sciences (or) Public Health. Qualification & Experience (Desirable) : 1. Diploma/ certificate in clinical research (or) One year of experience in clinical trials / clinical research. 2. Knowledge in basic computer applications. 3. Working knowledge of clinical study databases. 4. Good organizational skill. Job description : a. Assisting PI in the Recruitment of patients in the study as per the study protocol. b. Entry of patient data into the database. c. Follow-up of patients in the trial. Monthly emoluments : Rs. 30,000/- (Consolidated) Age limit as on 01/07/2024 : 35 Years Number of vacancies : Existing -1

Nature / Tenure of appointment : Temporary (Purely on contract), for a period of one year or till completion of the project, whichever is earlier.  Those who fulfil the above requirements may report for Interview, as per the above schedule at the Ground floor of AMCHSS building, along with Bio-data, original certificates and copies of certificates to prove age, qualification and experience at the time of interview.

Date & Time of interview : 09/07/2024,11:00 AM Time of Reporting : 10:00 AM Venue : AMCHSS Building, Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST) at Medical College Campus, Thiruvananthapuram. (adsbygoogle = window.adsbygoogle || []).push({});

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Nurse Practitioner - Advanced Illness Management

Job Posting for Nurse Practitioner - Advanced Illness Management at Empatia Palliative Care

  • Work in collaboration with the Professional Services Corporation (PSC) Physician or supervising physician, Primary Care Physician, and other palliative team members to deliver advanced illness management and palliative care by providing diagnosis, treatment and follow-up for patients referred to Empatia.
  • Take responsibility for advanced illness management from the initial assessment through discharge. Assessment at a minimum should include: disease-specific changes, decline or change in function, nutrition and/or cognition, inadequately controlled pain or other distressing symptoms, falls, infections or similar events, the impact of the disease burden on the patient's condition, caregiver and/or family's quality of life.
  • Establish the plan of care, individualized for each patient, in consultation with the patient, family and other members of the Advanced Illness team, to include the PCP.
  • Facilitate obtaining care for patient when a need is identified in accordance with the Plan of Care.
  • Participates in evening/weekend call as required, conducting on-call services in a clinically competent and responsive manner.
  • Prescribe medications including controlled substances to the extent delegated and licensed, in accordance with state law. Order and interpret laboratory, imaging and other diagnostic tests within the scope of professional practice. Order treatments and durable medical equipment as indicated.
  • Communicate clinical findings to the PSC Physician as needed, but no less than bi-weekly. Re-assess effectiveness of care plan on a regular basis and modify as needed.
  • Maintain effective working relationships with supportive care team (e.g., Social Worker and RN Care Manager), as applicable, and involve team (internally and externally) when patient's care plan warrants team participation to achieve desired outcome.
  • Establish and maintain effective working relationships with those contacted in the course of work.
  • Communicate and document clinical findings, treatment plan, and care provided in the patient's medical record in a manner consistent with acceptable standards in order to support sound medical practice and reimbursement for services provided.
  • Knowledgeable of Palliative Medicine Quality Measures collection, documentation and reporting.
  • Excellent leadership, interpersonal, written and verbal communication skills.
  • Independent decision making and self-motivation.
  • Working knowledge or understanding of: principles of Palliative Medicine, including when a patient may be appropriate for home health or hospice care; Medicare/Medicaid regulations; and interdisciplinary process; value based and/or accountable organization requirements
  • Meets mandatory continuing education requirements of Gentiva and licensing board.
  • Must be able to work efficiently with electronic medical record software.
  • Minimum of Masters of Science in Nursing from an accredited school of nursing, or an equivalent as allowed under state law
  • Minimum of two years Nurse Practitioner experience
  • Nurse Practitioner specialty in Family or Adult Medicine preferred
  • Value Based Care practice experience preferred
  • Practice experience with Part B billing
  • Able to work autonomously in an Advanced Practice Role
  • Current license as a registered nurse or equivalent as required by state law for Nurse Practitioner licensure
  • Current Nurse Practitioner certification/license
  • Collaborative agreement with a supervising physician, that is part of the Professional Services Corporation, that is agreeable to supervise work in advanced illness management and palliative care program, as required by state law
  • Part B Provider certification
  • Federal DEA license
  • State DEA license (if required)
  • ACHPN – Certification in Hospice and Palliative Care Preferred
  • Current automobile insurance and valid driver’s license
  • Competitive Pay
  • 401(k) with company matching contributions
  • Career growth opportunities available at both the branch and corporate levels
  • One on One Onboarding Program
  • Free Continuing Education Units
  • Local and national award programs
  • Referral bonus program
  • Mileage reimbursement
  • Financial assistance program supporting teammates in times of need
  • This is a safety-sensitive position
  • Employee must meet minimum requirements to be eligible for benefits
  • Where applicable, employee must meet state specific requirements
  • We are proud to be an EEO employer
  • We maintain a drug-free workplace

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$111,045 - $129,978

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Here’s What the Court’s Chevron Ruling Could Mean in Everyday Terms

The decision is expected to prompt a rush of litigation challenging regulations across the entire federal government, from food safety to the environment.

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Gray columns and a white flag on the front of a the Environmental Protection Agency building.

By Coral Davenport ,  Christina Jewett ,  Alan Rappeport ,  Margot Sanger-Katz ,  Noam Scheiber and Noah Weiland

  • June 28, 2024

The Supreme Court’s decision on Friday to limit the broad regulatory authority of federal agencies could lead to the elimination or weakening of thousands of rules on the environment, health care, worker protection, food and drug safety, telecommunications, the financial sector and more.

The decision is a major victory in a decades-long campaign by conservative activists to shrink the power of the federal government, limiting the reach and authority of what those activists call “the administrative state.”

The court’s opinion could make it easier for opponents of federal regulations to challenge them in court, prompting a rush of new litigation, while also injecting uncertainty into businesses and industries.

“If Americans are worried about their drinking water, their health, their retirement account, discrimination on the job, if they fly on a plane, drive a car, if they go outside and breathe the air — all of these day-to-day activities are run through a massive universe of federal agency regulations,” said Lisa Heinzerling, an expert in administrative law at Georgetown University. “And this decision now means that more of those regulations could be struck down by the courts.”

The decision effectively ends a legal precedent known as “Chevron deference,” after a 1984 Supreme Court ruling. That decision held that when Congress passes a law that lacks specificity, courts must give wide leeway to decisions made by the federal agencies charged with implementing that law. The theory was that scientists, economists and other specialists at the agencies have more expertise than judges in determining regulations and that the executive branch is also more accountable to voters.

Since then, thousands of legal decisions have relied on the Chevron doctrine when challenges have been made to regulations stemming from laws like the 1938 Fair Labor Standards Act, the 1970 Clean Air Act , the 2010 Affordable Care Act and others.

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Election latest: Reform candidate disowns party amid racism row - and backs Tories

Rishi Sunak says Labour would cause "irreversible damage within just 100 days of coming to power" led by Sir Keir Starmer. Meanwhile, Nigel Farage faced questions from Trevor Phillips on racist comments made by a Reform canvasser.

Sunday 30 June 2024 19:01, UK

  • General Election 2024

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  • Reform candidate disowns party amid racism row - and backs Tories | Which comes after party dropped three candidates
  • Farage says he 'doesn't want to know' racists | And finally rules out joining Tory party after election
  • Sunak insists he can still win election
  • Has Labour chosen wealthy pensioners over children in poverty?
  • 'Extremely troubling' footage emerges of Tory association students singing Nazi song | But party says group 'not affiliated' to them
  • Rob Powell:  With more coverage comes more scrutiny
  • Politics at Jack and Sam's : The last weekend
  • Live reporting by Ben Bloch  and (earlier)  Faith Ridler

Election essentials

  • Manifesto pledges: Conservatives | Greens | Labour | Lib Dems | Plaid | Reform | SNP
  • Trackers:  Who's leading polls? | Is PM keeping promises?
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  • Read more:  Who is standing down? | Key seats to watch | What counts as voter ID? | Check if your constituency is changing | Guide to election lingo
  • How to watch election on Sky News

Our daily politics show  Politics Hub  is live now on Sky News with our  political correspondent  Ali Fortescue  hosting this evening.

The fast-paced programme dissects the inner workings of Westminster, with interviews, insights, and analysis - bringing you, the audience, into the corridors of power.

Tonight will be a slightly different show, as we take in reaction to the result England's Euros match against Slovakia (when it concludes after extra time), and also the exit poll from the French parliamentary elections.

To discuss the Euros, we will be joined by our correspondents in Germany and here in the UK.

To dissect the French election, we will be joined from Paris throughout the show by  French political commentator Agnes Poirier .

And as the UK general election campaign enters its final days, we will speak to  Treasury minister Bim Afolami .

On Ali's panel are:

  • Luisa Porritt , former Lib Dem MEP;
  • Lucy Fisher , Whitehall editor at the Financial Times.

Watch live on Sky News, in the stream at the top of this page, and follow live updates here in the Politics Hub.

Watch  Politics Hub  from 7pm every night during the election campaign on Sky channel 501, Virgin channel 602, Freeview channel 233, on the  Sky News website  and  app  or on  YouTube .

Rishi Sunak has described Nigel Farage as a "Putin appeaser" - but speaking to our  political editor  Beth Rigby  today, the Reform UK leader labelled it "a load of cobblers".

But he said Ukraine should enter peace talks with Russia, saying: "Wars end in two ways - either one side gets annihilated, literally annihilated, as happened, of course, to Germany in 1945, or there are negotiations."

He said he is "anti-war" and "against the warmongering parties of Labour and Conservative over the last 25 years".

He acknowledged that Russia will have to return the territories it has forcibly taken from Ukraine, saying it "has to happen".

But he added: "I really do fear for what is going to happen to Ukraine, if this goes on for another three or four years."

Nigel Farage has previously described social media personality Andrew Tate as an "important voice" for men.

Sky's  political editor  Beth Rigby  asked him about the comment in an interview earlier, and he repeated that Tate is a "huge voice for men".

The Reform UK leader added: "Doesn't mean I agree with him in any way at all. Doesn't mean that I'm not horrified by seeing some of the charges and the extradition that's probably going to happen."

Andrew Tate, along with his brother Tristan, have been charged with allegations of rape, human trafficking and forming a criminal gang - charges they deny.

But Mr Farage said he remains an important voice for young men, saying: "Why do you think he's got the massive following he's got? What do you think's going on here?

"And there are so many young men feeling that they aren’t allowed to be blokes in any way at all, and that's the gap that Tate is filling.

"And this is the problem, isn't it?"

He added that he does not support Tate "in any way at all", and the support he has "should worry you".

Our daily politics show  Politics Hub  will be live on Sky News from 7pm with our  political correspondent  Ali Fortescue  hosting this evening.

Tonight will be a slightly different show, as we take in reaction to the result England's Euros match against Slovakia, and also the exit poll from the French parliamentary elections.

To dissect the French election, we will be joined from Paris throughout the show by French political commentator Agnes Poirier .

And as the UK general election campaign enters its final days, we will speak to Treasury minister Bim Afolami .

In the undercover report from Channel 4 looking at Nigel Farage's activists, one of them made comments deemed homophobic.

A close aide to the Reform UK leader said when a police car passed that displayed a pride flag: "You see that f****** degenerate flag on the front bonnet? What are the old bill doing promoting that crap? They should be out catching nonces, not promoting the f******."

Asked what he made of those comments by Sky's political editor Beth Rigby , Mr Farage said: "Yeah, on the point the police should not show political symbols, agreed. On the point they should be doing stop and search. Agreed. Of course, I agree with that totally.

"On the language that was used - crass, drunken, vulgar, rude, wrong."

He said he was "very angry" and "furious" when he heard that his aide had made the comment because he "didn't expect him to do it".

Mr Farage said: "The football was on, and he was down a few drinks. We could all say silly things when we're a bit half cut."

Beth challenged him on that, but Mr Farage insisted that "people say all sorts of things when they're drunk and often don't even remember it the next day".

But he added: "It was, it was awful."

Rishi Sunak spoke this afternoon at the Machzike Hadath Synagogue in Golders Green, north London, and told the congregation that a government under his leadership will stand behind Israel.

Recalling the "horror" of the 7 October Hamas attack on Israel, he said he will "never equivocate on who was to blame for this ugly, abhorrent act of terror".

"I will be steadfast in standing by Israel in its time of need, and I will not try and bully Israel into making concessions that are not in its interests. Israel deserves to live in peace and security."

He called for Hamas to release the Israeli hostages still being held in Gaza.

The PM also referenced Iran's attack on Israel in April, saying: "I am proud that I'm the first British prime minister to have ordered our military into action to protect the state of Israel, and I'm even prouder of the role our military played in ensuring Iran's missile and drone barrage did not succeed."

Mr Sunak also criticised the "shocking increase in antisemitism" in the UK since the 7 October attacks, and hit out at those who "blame Israel for defending itself, for doing what any state would do in response to such a horrific, barbaric attack".

"The whole fabric of our nation is under threat. This antisemitism is a sickness, and I am determined to confront it."

He pledged to "lead a long term effort" to do so, and "change our culture so we tackle the root causes of this hatred".

The PM said, if re-elected, he would "tell the police to take a zero tolerance approach to antisemitic hate crimes".

Finally, Mr Sunak hit out at Labour's plan to add VAT to private school fees, saying: "It is particularly wrong to put VAT on the fees of Jewish schools when there is not sufficient alternative provision in the state sector.

"Your values, education, hard work and enterprise are very British values, and they are also Conservative values."

By Adam Boulton , Sky News commentator

Becoming prime minister is a shock. Not so much the moment of being elected - any sensible democratic politician knows that opinion polls can be wrong and gets ready for all eventualities.

No incoming prime minister can ever be fully prepared for the demands of the job, placed on them from day one, when - among many other demands - they are taken aside to be briefed about their role in a nuclear war.

The process is particularly challenging in the UK because the change is so quick. There are no weeks of transition, as in most other countries. Nobody else does it like us.

As Tony Blair remarked to Alastair Campbell: "Imagine preparing for a new job by working flat out travelling the country for six weeks and then go a few nights without sleep."

If this general election goes to usual form either Prime Minister Keir Starmer or Prime Minister Rishi Sunak will be installed in 10 Downing Street by lunchtime the day after the vote.

Neither of them will have had any sleep the night before, waiting for the declarations in their own constituencies into the small hours, and then dealing with the fallout from the results elsewhere.

Read Adam's full piece here:

Nigel Farage has finally ruled out joining the Conservative Party after the general election after weeks of failing to give a categorical answer.

Just two weeks ago, the Reform UK leader repeatedly sidestepped questions from Sky's deputy political editor Sam Coates , saying he did not know what he would be having to eat in five years time, called the question "moronic" and said he had no intention of joining the Tories.

But he refused time and time again to give a more categorical answer.

Speaking to Sky's political editor Beth Rigby today, however, he finally said he would not seek to join the Tories.

He described the party as "ghastly", saying: "They betrayed the 2019 election result, Brexit voters. They have no interest in the truth. For them, it's all a game about being in power. [I have] no interest."

Pushed by Beth on if he would rule out joining the Tories, he said: "This [Reform UK] is a new political movement. I want nothing to do with them."

Asked again, Mr Farage did rule it out, saying: "If you don't work out that's a yes, I don't know what else I've got to say."

By Matthew Thompson, political correspondent

The finish line is in sight. Most of us, politicians and journalists alike, have been on the road for weeks.

Batteries are running low. And yet, Sir Ed Davey's enthusiasm for hurling himself into the nearest body of water remains undimmed. The Lib Dems have a strategy, and they're sticking to it.

Which therefore begs the question: is that strategy actually working?

Such things are hard to measure. But polling data, as well as admittedly less scientific chats with the voting public, suggest it isn't exactly doing him any harm.

"I mean, it's entertaining," says Charlotte, watching Sir Ed prance around with a water noodle in the Cheltenham Lido.

"I don't know how much it really affects my political view, but he's likeable. He seems more relatable."

"I suppose it's a bit of fun really," says Joan, another onlooker. I ask her whether she rates the Lib Dems' chances of winning here, and she replies: "I’d like to think so, but I think possibly not."

According to Ipsos, a pollster that tracks party leader popularity, Sir Ed's personal satisfaction ratings have risen seven points since early June. 30% of people are satisfied with him, whilst 35% are not.

If a net satisfaction rating of -5 seems low, it's worth comparing it to others, with Sir Keir Starmer (-19) and Rishi Sunak (-55) lagging far behind.

The Lib Dems as a party also seem to be performing well, with seat predictions uniformly suggesting considerable gains on the 15 MPs they had before the election. Although this could easily be a function of Tory unpopularity as much as enthusiasm for the Lib Dems.

And speaking to journalists in Cheltenham today, a key Lib Dem target, Sir Ed said the party has expanded the number of seats it thinks are winnable, particularly in the South West of England.

His own constituency visits have suggested a similar pattern, with a trend towards visiting seats that would require larger swings to the Lib Dems.

So the mood on the big yellow bus is about as buoyant as Ed Davey in his customary life jacket. The stunts will keep coming.

But as politicians are fond of repeating, there's only one poll that counts. And there are still four days to go.

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