Mean age: 41.9 years
BPI, Brief Pain Inventory; MPQ, McGill Pain Questionnaire; NDI, Neck Disability Index; NRS, Numeric Rating Scale; ODI, Oswestry Disability Index; PDI, Pain Disability Index; PIPT, psychologically informed physical therapy; PSFS, Patient Specific Functional Scale; RMDQ, Roland Morris Disability Questionnaire; VAS, visual analog scale.
Graded exposure specifically targets activities or tasks that a patient is fearful of due to perceived risks of harm or the pain-related fear that contributes to avoidant behavior. 84 , 85 Patients work with a physical therapist to initially rate their level of fear toward these activities. Patients work in treatment to progressively approach or “confront” feared stimuli in a hierarchical model. Graded exposure proceeds with activities that elicit the least amount of fear and after task mastery, progresses towards those that are most feared. Progression within graded exposure occurs based on changes in fear after exposure, where patients learn that fears may be exaggerated, 30 or a sense of mastery and increased self-efficacy to approach previously avoided tasks. There are 2 mechanisms underlying graded exposure: (1) behavioral mechanism based on habituation to feared stimulus and positive reinforcement for successful completion, and (2) cognitive mechanism based on disconfirmation of fear-based predictions leading to cognitive restructuring. In a trial by Ariza-Mateos et al. 3 among patients with chronic pelvic pain, graded exposure added to manual therapy resulted in greater short-term improvement in disability and pain compared to a manual therapy alone (Table (Table2). 2 ). An introductory session of pain education was included as part of the graded exposure intervention. Therapist training was not described; however, the provider who delivered graded exposure was experienced with the approach. In terms of dosage, patients received graded exposure as an additional weekly 45-minute session of therapy over the 6-week period in addition to the manual therapy sessions.
Cognitive-behavioral therapy (CBT) is a widely known and effective psychological intervention for chronic pain. 89 The premise of CBT is that cognitive and behavioral factors, including a person's thoughts, beliefs, and actions, play a key role in the development or maintenance of chronic pain. 78 Cognitive-behavioral therapy provides patients with a repertoire of techniques to improve self-management of pain, enhance patient confidence in their ability to manage pain, and increase perceived control over pain. 5 Cognitive-behavioral therapy techniques aim to identify and decrease maladaptive behaviors, bolster positive coping, address dysfunctional thoughts and beliefs influencing pain, and increase confidence in pain self-management. Although specific techniques vary from clinician-to-clinician, components typically include elements of education, skill training (ie, goal setting, activity pacing, relaxation techniques [eg, deep breathing] or distraction, and problem solving), and skill application and maintenance in the patient's daily life. 24
Nine trials examined a cognitive-behavioral-based physical therapy approach (Table (Table3). 3 ). There was a range of CBT components across the physical therapy interventions, with most including education, goal setting, problem solving, and pain-coping skills. In all trials, physical therapists were trained to deliver the psychological-based intervention—mostly through workshop format and some offering ongoing supervision or feedback from a psychologist. Four trials compared cognitive-behavioral-based physical therapy to standardized exercise, 10 , 40 , 76 , 77 whereas 5 trials compared to a multimodal (eg, manual therapy and exercise) or pragmatic rehabilitation program. 44 , 61 , 72 , 81 , 82
Summary of recent cognitive-behavioral-based physical therapy studies.
Study | Sample | PIPT intervention | Standard PT intervention | Outcomes | Summary results |
---|---|---|---|---|---|
Bennell et al. | 222 patients (133 females) with chronic knee osteoarthritis Mean age: 63.4 years | involved 10 physical therapist-delivered modules covering pain education and cognitive and behavioral pain-coping skills and application. Pain-coping skills included activity-rest cycling, pleasant activity scheduling, problem solving, addressing negative thoughts, pleasant imagery, counting backwards, and auditory stimulation. Patients were encouraged to practice skills. Patients attended 10 individual sessions over 12 weeks. Each session lasted 45 minutes. (as described in other groups) were integrated. Patients attended 10 individual sessions over 12 weeks. Each session lasted 70 minutes. | included 6 strengthening exercises for the lower-extremity muscles. Patients were provided weights, elastic bands, and handouts for home use. Patients were instructed to perform exercises 4 times per week for 12 weeks and 3 times per week thereafter. Patients attended 10 individual sessions over 12 weeks. Each session lasted 25 minutes. | Physical function: WOMAC function Pain intensity: VAS (0–100) Pain: WOMAC pain Measured at 12, 32, and 52 weeks | The combined pain-coping skills training and exercise group showed greater improvement in physical function at 12 and 32 weeks compared to exercise. At 12 weeks, there were no significant differences between groups for overall pain intensity. However, the pain-coping skills training and exercise showed greater reductions in walking pain intensity than exercise. At 32 weeks, the combined group also showed greater improvement in pain intensity and WOMAC pain. |
Hunt et al. | 20 patients (12 females) with chronic knee osteoarthritis Mean age: 62.5 years | included a combined intervention of online pain-coping modules and home exercises. Pain-coping skills training involved 10 physical therapist-delivered modules covering pain education and cognitive and behavioral pain-coping skills and application. Pain-coping skills included activity-rest cycling, pleasant activity scheduling, problem solving, addressing negative thoughts, pleasant imagery, counting backwards, and auditory stimulation. Exercises included 6 strengthening exercises for the lower-extremity muscles and a preplanned walking program. Patients were provided weights, elastic bands, and handouts for home use. Patients attended 10 weekly individual sessions for pain-coping skills training and exercise. | included the same exercise intervention as the pain-coping group. In addition, patients participating in open discussions with the therapist to discuss any osteoarthritis-related problems. Specific advice was not provided by the therapist. Patients attended 10 weekly individual sessions for nondirective counseling and exercise. | Physical function: WOMAC function Pain intensity: NRS (0–10) Pain: WOMAC pain Measured at 11 weeks | No significant differences in physical function or pain between groups were observed. |
Lee et al. | 47 patients (23 females) with acute or subacute low back pain Mean age: 37.3 years | included a physical therapy program focused on physical function and based on cognitive-behavioral principles. Treatment included graded activity, pacing techniques, work conditioning, return to work goal setting, self-management, job analysis, and ergonomics. Cognitive-behavioral-based work rehabilitation could last up to 3 months. | included conventional individual physical therapy based on symptom presentation and response. Treatment could include a combination of modalities (interferential therapy, transcutaneous electrical nerve stimulation, traction), manual therapy, and exercise. Work rehabilitation could last up to 3 months. | Disability: RMDQ, ODI Pain intensity: NRS (0–10) Measured at discharge | No significant differences in disability or pain intensity between groups were observed. |
Monticone et al. | 80 patients (60 females) with chronic neck pain Mean age: 49.6 years | involved the same multimodal exercise program as the physical therapy group. In addition, physical therapists included cognitive-behavioral strategies to address patient beliefs, thoughts, and behaviors. Strategies included graded activity, addressing escape and avoidance behaviors, pain and fear-avoidance model education, coping and pacing skills, and graded exposure. Patients attended up to twelve 45–50-minute individual sessions, scheduled once or twice per week, for a maximum of 12 weeks. | included a multimodal approach of active and passive mobilization, postural control, stretching and strengthening exercise, and ergonomic advice. Patients were discouraged to receive other pain management treatments (ie, pain medication, physical modalities). Patients attended up to twelve 45–50-minute individual sessions, scheduled once or twice per week, for a maximum of 12 weeks. | Disability: NPDS Physical function: SF-36 Pain intensity: NRS (0–10) Measured at 3 and 12 months | No significant differences in disability, physical function, or pain intensity between groups were observed. |
Reid et al. | 588 patients (410 females) with mixed musculoskeletal pain Mean age: 73.0 years | included a 5-session cognitive-behavioral self-management program that was implemented within home care physical therapy. The sessions focused on topics including pain theory, becoming more active, relaxation, deep breathing, imagery, pleasant activity scheduling, activity pacing, sleep tips, and managing flare ups. Patients were provided a booklet reinforcing program content and encouraged to practice techniques on their own. Home care was delivered in a pragmatic manner under the direction of the physical therapist. | included pragmatically delivered care within the patient's home. Physical therapists completed a comprehensive functional assessment and evaluation of psychological functioning, home environment, and use or need of assistive devices. A treatment plan was generated and exercise was prescribed to increase strength, reduce fall risk, and improve motion, gait, transfer skills, balance, coordination, and functioning. Home care was delivered in a pragmatic manner under the direction of the physical therapist. | Disability: RMDQ Physical function: Functional status scale Pain intensity: NRS (0–10) Measured at 60 days | No significant differences in disability, physical function, or pain intensity between groups were observed. |
Sterling et al. | 108 patients (67 females) with acute whiplash-associated disorder Mean age: 41.3 years | combined 6 sessions of cognitive-behavioral-based training with the same 6-week exercise program as the exercise group. Stress inoculation training facilitated problem solving and coping strategies for managing stress-related anxiety. Physical therapists taught patients strategies to identify and understand stress, develop skills for managing stress, and apply skills in different situations. Patients attended ten 50-minute sessions over a 6-week period for stress inoculation training and exercise. | included progressive, individualized exercises to improve movement, strength, and endurance of the neck and shoulder girdle region, and to improve eye/hand coordination. Physical therapists also provided advice on return to normal activities and aerobic exercise. Manual therapy was allowed at the therapist's discretion. Patients attended ten 50-minute exercise sessions over a 6-week period. | Disability: NDI Physical health: SF-36 Pain intensity: NRS (0–10) Measured at 6 weeks, and 6 and 12 months | The stress inoculation training and exercise group showed greater improvement in disability and pain intensity at all time points after intervention. There was no significant difference in physical health between groups. |
Thompson et al. | 57 patients (26 females) with chronic neck pain Mean age: 47.5 years | included the same exercise program as the exercise group and an IBMT. The program aimed to reduce catastrophizing and pain-related fear and improve self-efficacy through interactive sessions challenging unhelpful thoughts, emotions, and beliefs. Physical therapists facilitated cognitive-behavioral strategies such as goal setting and problem solving. The cognitive-behavioral intervention was delivered in small groups. Patients attended four 90-minute weekly sessions for the cognitive-behavioral intervention and exercise. | included progressive, higher-intensity neck exercises to improve strength, mobility, and endurance. Exercises included cervical isometrics, resisted motion, and stretching. Written information describing that there was no serious cause of neck pain and outlining chronic cycle of neck pain was provided to patients. Patients attended four 40-minute weekly sessions. | Disability: NPQ Pain intensity: NRS (0–10) Measured at 6 months | There was no significant difference in postintervention disability between groups. The cognitive-behavioral groups showed a greater reduction in pain intensity. |
van Erp et al. | 25 patients (14 females) with chronic low back pain Mean age: 44.0 years | included a structured 12 session program (Back on Track) that stimulated patients to gain insight on pain mechanisms, behavior and beliefs, coping styles, goal setting, and self-management strategies. Graded activity and exposure were also included. Patients received a workbook with homework assignments. Patients attended four 30-minute individual sessions and eight 60-minute group sessions. | included individualized physical therapy based on best practices and guidelines for low back pain. Therapeutic strategies included manual therapy, core stability, and back strengthening. Physical therapists directed the frequency, duration, and content of sessions. Patients attended a maximum of 12 sessions of physical therapy. | Disability: QBPDS Pain intensity: NRS (0–10) Measured at postintervention and 3 months | No significant differences in disability or pain intensity between groups were observed. |
Vibe Fersum et al. , | 121 patients (63 females) with chronic low back pain Mean age: 41.5 years | was an individualized classification approach that addressed cognitive, movement, and lifestyle behaviors. Physical therapists based targeted strategies on the patient's initial presentation and psychosocial risk. Four components of the treatment included cognitive, specific movement, targeted functional integration, and physical activity. Cognitive strategies within the intervention included pain and fear-avoidance education, problem solving, goal setting, reflective communication, self-management, functional enhancement, and goal orientation. Patients attended weekly sessions for the first 2–3 weeks and then 1 session every 2–3 weeks for the 12-week duration. | included spine or pelvis manipulation or mobilization, general exercise, and/or motor control exercise. Inclusion of particular techniques or exercises, and dosage of procedures was based on the discretion of the treating therapist. Patients attended a 1-hour initial evaluation and 30-minute follow-up sessions. | Disability: ODI Pain intensity: NRS (0–10) Measured at 12 weeks, 12 months, and 3 years | There were significant differences in disability and pain at 12 weeks and 12 months between groups, with lower disability and pain scores after cognitive functional therapy. There was a significant difference in disability at 3 years between groups, with lower disability scores after cognitive functional therapy. No significant differences in pain between groups at 3 years were observed. |
IBMT, interactive behavioral modification program; NDI, Neck Disability Index; NPDS, Neck Pain and Disability Scale; NPQ, Northwick Park Questionnaire; NRS, Numeric Rating Scale; ODI, Oswestry Disability Index; QBPDS, Quebec Back Pain Disability Score; PIPT, psychologically informed physical therapy; RMDQ, Roland Morris Disability Questionnaire; VAS, visual analog scale; WOMAC, Western Ontario and McMaster Universities Osteoarthritis Index.
Five trials reported no difference between the cognitive-behavioral-based physical therapy group compared to control. 40 , 44 , 61 , 72 , 81 Of these 5 trials, 4 trials included a control group of multimodal or pragmatic rehabilitation, 44 , 61 , 72 , 81 whereas the remaining trial was a small pilot study. 40 In the small pilot study of 20 patients, Hunt et al. 40 established the feasibility of a pain-coping skills training program that was later tested in a larger randomized trial. In trials by Lee et al. 44 and Reid et al., 72 the cognitive-behavioral intervention was developed for utilization within distinctive settings of work rehabilitation and home health care, respectively.
Studies by Bennell et al., 10 Sterling et al., 76 Thompson et al., 77 and Vibe Fersum et al. 82 , 83 showed greater efficacy after cognitive-behavioral-based physical therapy for an outcome of function, disability, or pain. Bennell et al. 10 and Thompson et al. 77 showed greater short-term efficacy compared to a standard therapy group, whereas Sterling et al. 76 and Vibe Fersum et al. 82 , 83 reported greater efficacy in disability and pain at 1 year (or longer for Vibe Fersum et al.). In a 3-arm randomized trial by Bennell et al., 10 a 12-week, 10-session pain-coping skills training program combined with exercise resulted in greater effects on physical function up to 32 weeks compared to a group consisting of exercise alone for patients with knee osteoarthritis. There were duration differences between groups, with the pain-coping skills and exercise sessions lasting 70 minutes per session and the exercise only group lasting 25 minutes per session. Therapist training for delivering the pain-coping skills intervention was rigorous involving a 4-day workshop, therapist accreditation, ongoing supervision, and feedback provided by an experienced psychologist.
Sterling et al. 76 and Thompson et al. 77 examined a cognitive-behavioral-based physical therapy intervention for patients with cervical spine conditions. Sterling et al. 76 provided 10 sessions over 6 weeks of stress inoculation training—a cognitive-behavioral approach focused on helping patients manage stress-related anxiety—to patients with acute whiplash-associated disorder and found greater treatment efficacy in disability and pain up to 1 year. The target sample was patients at risk for poor recovery with moderate disability (based on Neck Disability Index) and hyperarousal symptoms (based on Posttraumatic Stress Diagnostic Scale) at initial presentation. Duration was matched at 50-minute sessions for both stress inoculation with exercise and exercise alone groups. Similar to the study by Bennell et al., 10 Sterling et al. 76 used a psychologist and physician-led workshop, therapist accreditation, and a training booster session. Thompson et al. 77 combined interactive behavioral modification therapy with progressive exercises for patients with chronic neck pain. Thompson et al. 77 did not find differences in disability between the interactive behavioral modification therapy with exercise and exercise groups but did report greater pain reduction in the intervention group. Patients in the behavioral therapy group required more time with physical therapists (90 minutes per session) compared to the exercise group (40 minutes per session). Specific training for the interactive behavioral modification therapy was not described; however, therapists who delivered this intervention were reported to have prior experience in delivering pain management programs.
Vibe Fersum et al. 82 , 83 examined a 12-week classification-based cognitive functional therapy approach for chronic low back pain. The distinction with this method compared to previously mentioned PIPT approaches is the use of a classification system. In this system, patient characteristics were used to inform the specific strategies implemented within treatment, providing a targeted or tailored therapy approach. The cognitive functional therapy intervention included 4 components targeting cognitive, specific movement, functional integration, and physical activity. Compared to manual therapy and exercise, patients receiving classification-based cognitive functional therapy showed greater improvement in disability and pain up to 1 year. A follow-up study by Vibe Fersum et al. 83 reported that group differences persisted at 3 years for disability, but not pain intensity. Total number and duration of sessions were similar for each group. Physical therapists delivering the cognitive functional therapy had substantial training and experience (eg, average of 106 hours of training) in this method.
As can be seen from the previous studies, CBT has been the prime intervention underlying PIPT. This is largely based on the evidence of effectiveness for CBT in chronic pain. 89 Acceptance and commitment therapy (ACT) is a “third wave” cognitive-behavioral intervention initially developed for psychological disorders. 59 , 74 However, ACT has a growing evidence base for addressing chronic pain. 39 Acceptance and commitment therapy uses techniques including mindfulness, acceptance, and behavioral change strategies to increase internal flexibility and help patients reconnect with core values to lead more fulfilling lives in the presence of chronic pain. 39 Recognizing that some aspects of the chronic pain experience cannot be altered, ACT shifts focus on pain or symptom reduction towards promoting “acceptance” and simultaneous patient achievement of value-oriented goals such as improved physical functioning. The aim of ACT is to reduce experiential avoidance (avoiding unwanted sensations, thoughts, and emotions) and promote psychological flexibility through openness (acceptance and cognitive defusion [seeing thoughts as mental events that come and go, without letting them drive behavior]), awareness (present-moment contact and self-as-context [being able to observe internal experiences without identifying with them]), and activity engagement (clarifying values and committed action). 25
One study by Godfrey et al. 32 has evaluated a physical therapy approach informed by acceptance and commitment therapy (PACT) (Table (Table4). 4 ). The PACT intervention was a brief intervention spanning 3 individual visits (eg, two 1-hour in-person visits and one 20-minute telephone session) over 1 month. The strategies implemented within PACT aimed to promote self-management and psychological flexibility. 31 Specific strategies included shifting focus, value-based goal setting and adjustment, mindfulness exercises, action plans, identification of support system, and skills application. At 3 months, patients receiving PACT compared to usual physical therapy had greater improvement in disability, physical function, and physical health. This difference was not maintained at 1 year. There was no difference in pain intensity ratings between groups at any time point, which could be expected, given the PACT focus on functioning as opposed to reductions in pain. Physical therapists involved in delivering PACT were initially trained in a 2-day workshop led by psychologists with expertise in ACT and were required to apply the intervention with practice patients. 31 , 32 Workshop training involved education, experiential exercises, role playing, and problem solving. Supervision, feedback, and assessment of skill were provided by the team of trainers and further training was delivered as needed. Qualitative reports by the physical therapists indicated that PACT was feasible and acceptable. Although adherence to PACT was high, Godfrey et al. 53 noted that only a few ACT methods were delivered by physical therapists across sessions. The total mean total duration of therapy time was marginally less than usual physical therapy (2 hours compared to 3 hours).
Summary of recent acceptance and commitment-based physical therapy studies.
Study | Sample | PIPT intervention | Standard PT intervention | Outcomes | Summary results |
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Godfrey et al. | 248 patients (147 females) with chronic low back pain Mean age: 47.9 years | was a self-management promoting intervention that included two 1-hour in-person treatment sessions (2 weeks apart) and one 20-minute phone call (1 month later). PACT included an initial physical assessment, identification of value-based goals, individualized exercise, addressing of self-management barriers and facilitators, and psychological flexibility skills training. No manual therapy was included. | included standard physical therapy treatment that could include individual physical therapy or back rehabilitation classes, dynamic control classes, manual therapy, or hydrotherapy. Physical therapy was directed by the providing physical therapists. | Disability: RMDQ Physical function: PSFS Physical health: SF-12 Pain intensity: NRS (0–10) Measured at 3 and 12 months | The PACT group showed greater improvement in disability and physical function compared to physical therapy at 3 months. No significant differences were noted at 12 months In addition, there were no differences in pain between groups at 3 or 12 months. |
NRS, numeric rating scale; PACT, physical therapy approach informed by acceptance and commitment therapy; PIPT, psychologically informed physical therapy; PSFS, Patient Specific Functional Scale; RMDQ, Roland Morris Disability Questionnaire.
The advanced training and clinic session time required to deliver specific CBT or ACT-based strategies are potential barriers to PIPT implementation. Moreover, physical therapists may struggle with delivering psychological strategies because these may be perceived as out of their scope of practice or comfort level. 6 Internet-based psychological programs (or applications) for pain offer a potential solution for providing PIPT in a more scalable manner, especially when integrated with therapy. 11 Several widely available programs exist and have been presented in the literature.
Two studies have examined the efficacy of combining internet-based psychological programs with physical therapy (Table (Table5). 5 ). Petrozzi et al. 69 randomized patients undergoing physical therapy (or chiropractic care) to receive access to MoodGYM—a free, noncondition-specific, 5-module CBT-based program that addresses patient's thoughts, feelings, and stressors. The authors reported no added benefit of including MoodGYM above what was reported by patients receiving physical therapy alone. 69 It is possible that the lack of specificity of the program or poor adherence, which was not objectively tracked in the trial, could have impacted findings. In addition, MoodGYM was not integrated as part of clinical treatment. In other words, providers did not seem to reinforce program content or help patients apply the skills learned. This was a similar approach taken by Bennell et al. 12 who had patients' access and complete PainCOACH, an interactive 8-module program emphasizing pain-coping skills, before undergoing a standard exercise program for hip pain. Similar long-term clinical outcomes were observed compared to internet education and standard exercise. The lack of integration by Bennell et al. 12 enhanced methodological rigor (ie, blinding of therapists), 13 but may explain the lack of added long-term benefit.
Summary of PIPT studies with use of internet-based programs.
Study | Sample | PIPT intervention | Standard PT intervention | Outcomes | Summary results |
---|---|---|---|---|---|
Bennell et al. | 144 patients (82 females) with chronic hip osteoarthritis | included the same internet-based education and home exercise program as the control group. In addition, pain-coping skills training included 8 online modules that patients accessed during the first 8 weeks of the intervention. Pain-coping skills modules covered relaxation, activity-rest cycling, pleasant activity scheduling, cognitive restructuring, pleasant imagery, distraction, and problem solving. Patients were reminded weekly to complete modules. | included 8 information sheets related to arthritis self-care that were provided over the first 8 weeks of the intervention. Topics covered arthritis, pain, physical activity, saving energy, healthy eating, emotions, and tips for hip osteoarthritis. Patients were instructed to access 1 sheet per week. Exercise included a home-based exercise program that patients performed 3 times per week from weeks 8–24. Patients attended five 30-minute sessions with a physical therapist every 3 weeks. A physical therapist prescribed individualized strengthening exercises for the lower extremity and hip stretching. | Physical function: WOMAC function Pain intensity: VAS (0–100) Pain: WOMAC pain Measured at 8, 24, and 52 weeks | The internet-based pain-coping skills group showed immediately greater improvements in physical function at 8 weeks compared to control. This effect did not persist at 24 or 52 weeks. No significant differences in pain between groups were observed after intervention. |
Petrozzi et al. | 108 patients (54 females) with chronic low back pain Mean age: 50.4 years | included the same physical treatment as the comparison group. Patients attended up to 12 sessions at a frequency and duration based on clinical judgment and patient response. In addition, patients received access to online cognitive-behavioral program (MoodGYM). The program included 5 modules that explore thoughts, feelings, stressors, and relationship that contribute to psychosocial distress, and promotes strategies for coping and problem solving. Patients were instructed to access 1 module per week while attending physical treatment. No in-person counseling was provided as part of the intervention. | included pragmatically applied techniques such as spinal manipulation, mobilization, soft tissue massage, and exercise. Patients also received reassurance, advice about symptom management, instruction on safe manual handling, general postural advice, and encouragement to stay active. Physical treatment was provided by a physical therapist or chiropractor. Patients attended up to 12 sessions at a frequency and duration based on clinical judgment and patient response. | Disability: RMDQ Physical function: PSFS Pain intensity: NRS (0–10) Measured at 8 weeks, and 6 and 12 months | No significant differences in disability, physical function, or pain intensity between groups were observed after intervention. |
NRS, numeric rating scale; PIPT, psychologically informed physical therapy; PSFS - Patient Specific Functional Scale; RMDQ, Roland Morris Disability Questionnaire; VAS, visual analog scale; WOMAC, Western Ontario and McMaster Universities Osteoarthritis Index.
4.1. summary of findings.
Summary findings from recent trials point to a few important observations. First, there continues to be evidence that graded activity is not a superior approach for chronic low back pain compared to other forms of exercise. This has been highlighted in earlier systematic reviews of the literature. 46 , 51 , 80 In the current review, none of the included studies on graded activity showed greater efficacy in improving outcomes compared to standard physical therapy. Second, despite the apparent accessibility and feasibility, internet-based psychological programs provided to patients in physical therapy do not seem to contribute to better outcomes compared to physical therapy alone. Issues related to low adherence to the online program, lack of support or integration of learned skills within therapy, or issues with program specificity may explain the apparent lack of additional benefit. Finally, as often is the case, there are areas that lack clear conclusions.
Prior systematic reviews have summarized evidence on efficacy of graded activity 46 , 51 , 80 and PIPT. 1 , 17 , 33 , 75 , 90 Overall, our results are largely consistent with these reviews, which show promising effects for PIPT, namely in-person cognitive-behavioral-based physical therapy. Prior reviews have differed in their focus for condition (ie, postoperative pain, 17 general musculoskeletal pain, 1 , 75 low back pain, 33 and chronic pain 90 ) and comparators. We intended a broad condition focus that would include both nonoperative and postoperative patients, but did not find any postoperative studies that directly compared PIPT to standard physical therapy. A few notable postoperative PIPT studies that did not meet this specific criterion, but should be considered when determining the value of postoperative PIPT, include studies by Archer et al., 2 Lotzke et al., 47 Riddle et al., 73 Peolsson et al., 68 and Wibault et al. 88 Most of these postoperative studies compared a PIPT approach to usual postoperative care, which may have included physical therapy.
We did include similar PIPT studies as prior reviews, but also more recent trials. In contrast to prior reviews, we report summary findings related to ACT-based physical therapy and internet-based psychological programs offered in conjunction with physical therapy. These novel approaches have potential implications and can inform future directions. For example, CBT represents the most common psychological approach that has shaped PIPT. The evidence for cognitive-behavioral-based physical therapy is summarized in this review and in prior meta-analyses. 75 , 90 However, more recent psychological approaches such as ACT, mindfulness, and positive psychology may provide novel strategies to integrate within physical therapy. Our review suggests that ACT-based physical therapy may be a beneficial approach for chronic pain. 32 In the context of personalized medicine, targeted psychological strategies may need to consider not only psychological risk factors commonly addressed with CBT, but also whether boosting resiliency characteristics such as positive affect, hope, or optimism can translate to meaningful clinical outcome effects. 26 , 34
Results from recent studies examining in-person CBT-based physical therapy approaches are mixed. These findings may suggest a lack of robust superiority for PIPT compared to pragmatically delivered physical therapy. 65 It is possible that traditional physical therapy interventions such as exercise could impart similar benefits to psychological-based interventions through shared or nonspecific mechanisms. 60 Before settling on these conclusions, the quality of the randomized trials and the need to examine additional factors that may impact the role of this class of intervention should be considered. For example, half of the “positive effects” studies on cognitive-behavioral-based physical therapy were judged to be of lower methodological quality, which could bias these results. Studies demonstrating efficacy of cognitive-behavioral-based physical therapy tended to have larger sample sizes compared to trials showing no difference, suggesting a higher likelihood to detect small differences in outcomes. The exception was the study by Reid et al. 72 (>500 patients) that reported no difference in efficacy for cognitive-behavioral-based physical therapy. Reid et al. 72 acknowledge that their trial may have been affected by low psychological strategy implementation by physical therapists. The main implementation challenges were time to deliver the intervention (additional 15–20 minutes), which interfered with addressing other patient issues, and low utilization of written material or practice techniques by patients. High-quality studies by Bennell et al., 10 Sterling et al., 76 and Godfrey et al. 32 as well as the study by Vibe Fersum et al., 82 , 83 which show greater efficacy after cognitive-behavioral-based physical therapy, describe rigorous training and implementation protocols. Moreover, most of these trials involve collaboration with a clinical psychologist and/or rehabilitation physician, 10 , 76 which may be an important component of both training and fidelity.
Cognitive-behavioral therapy, delivered by psychologists, is an intervention with relatively good outcome effects for chronic pain. 22 If CBT-based interventions delivered by physical therapists are similarly efficacious as traditional therapy, this begs the question of why this may be the case. Unlike CBT, physical therapy is often not standardized or protocolized. Thus, there are no established dosage and content parameters that are widely accepted as effective. In the current review, we found variability in the structure of PIPT in terms of total number, frequency and duration of sessions, and length of the treatment program. We did not observe an apparent pattern that would describe the impact of these parameters on treatment efficacy. For example, Godfrey et al. 31 reported beneficial effects after their relatively brief PIPT intervention. Optimizing parameters related to PIPT dosage and content is an important area for further exploration.
Another possible reason for mixed or comparable outcome findings could relate to the lack of targeting of the PIPT to a population “at risk.” Few of the included studies directly targeted the PIPT intervention to patients exhibiting heightened psychosocial risk. One example of a trial that did was the study by Sterling et al. 76 where patients were screened for hyperarousal symptoms. Psychologically informed physical therapy strategies may not be needed by all patients with musculoskeletal pain. This approach of stratifying patients based on psychosocial risk is not new and there has been success with primary care pathways involving physical therapy for acute back pain. 36 There may be a role for personalized approaches to assess not whether PIPT works, but rather which patients benefit from these augmented rehabilitation treatments and who may not need them or respond. Recent evidence suggests a potential outcome influence for not only psychosocial risk factors, but also resiliency characteristics. 7 , 58 , 87 Future studies should examine whether complex psychological profiles including both risk and resiliency characteristics impact the efficacy of PIPT interventions.
The added cost and burden of integrating PIPT in real-world settings may not outweigh small degrees of additional benefits that have been observed in the literature. For most physical therapists, the PIPT approach represents a considerable shift from traditional physical therapy care. Transformative physical therapy practice may involve greater focus on addressing psychological risk factors, use of psychological techniques that might conflict with physical-focused interventions (in terms of time or priority), and/or adjustments to longer therapy sessions or group-based formats. Each of these practice shifts may come at a “cost” to the therapist or clinic. It was beyond the scope of this review to examine the cost implications (or savings) of a PIPT approach. However, as part of their trial, Bennell et al. 10 did report a higher cost of delivery for PIPT (pain-coping skills and exercise) due to the lengthier treatment sessions, but no difference in cost-effectiveness between groups. Godfrey et al. 32 found no major cost of delivery or utilization differences in their study, but did acknowledge the need for a one-off PIPT training cost. Thompson et al. 77 reported cost savings with their PIPT approach because of the small group format. Although a formal cost-effectiveness analysis was not conducted, Thompson et al. 77 did report no difference in healthcare utilization between groups. Future efforts examining costs supporting a PIPT model of care and cost-effectiveness are needed.
Qualitative reports emphasize physical therapist's concerns and barriers to approaching pain management in a PIPT manner. 38 There is inadequate training in psychological interventions or cognitive-behavioral pain strategies across entry-level physical therapy programs. 37 Postgraduate educational opportunities in PIPT are scarce and may not meet the rigor of training needed to support a PIPT practice model. 15 , 63 For example, successful behavioral intervention training programs often use multiple methods such as workshops, role playing, practice, supervision by a psychologist, and peer feedback to ensure intervention adoption and prevent drift. 35 Several of the described trials used these methods with study physical therapists and often, the results suggested high fidelity to delivering PIPT. Even when implementation rates are low, physical therapists demonstrate ability and confidence to provide PIPT techniques as trained. 72 One of the main challenges in transforming standard practice towards PIPT is the requirement to optimally train physical therapists in delivering cognitive-behavioral-based treatment. Currently, there is no widely accepted standard for PIPT intervention training. 42 Several high-quality studies included rigorous and comprehensive training programs that would be expected to be more effective in preparing physical therapists to deliver standard psychological strategies, but also manage patients with higher psychological burden or handle unanticipated challenges that may arise with this form of therapy. For example, periodic feedback from a psychologist and peer discussion have been important aspects to address unique patient experiences and challenges. 63 This aspect of training may not be feasible for all practice settings. Future research should aim to determine optimal and standardized methods to train, supervise, and monitor physical therapists' use of PIPT strategies.
Although some approaches such as graded activity or graded exposure can be integrated seamlessly into physical therapy, other strategies such as cognitive restructuring and relaxation techniques may require modifications to existing clinical treatment structures (ie, extended treatment time or use of private rooms). Several trials described in this review offered PIPT (with or without exercise) in sessions of 45-, 60-, or 90-minute durations. The increased time for a one-on-one, in-person clinical encounter may not be feasible in some outpatient practice settings and may not yield high likelihood for implementation. 72 There may be a need to examine which specific PIPT components or strategies are the most effective and aim to incorporate only those strategies within standard practice. To the best of our knowledge, there have not been any studies that have examined content optimization for PIPT. The examination of treatment components may require more advanced research designs that will identify the most “active” components of PIPT. 16
Internet-based programs have been developed to help overcome in-person treatment delivery challenges. To date, few studies have examined whether internet-based psychological programs can be integrated within an episode of physical therapy. The studies by Bennell et al. 12 and Petrozzi et al. 69 described PIPT approaches where physical therapists were not tasked with formally integrating internet content or skills, which may be a potential reason for the lack of additional benefit. Prior work in primary care has examined the impact of clinician support or contact on internet program utilization and efficacy. 19 Dear et al. 19 did not observe differences in clinical outcomes when an internet-based program was provided with no, optional, or regular clinician contact. Granted that the internet-based program is well developed and engaging, it is undetermined whether integration within physical therapy is needed. Future research should aim to expand on the current work described in this review to determine whether integrating internet-based programs can lead to more feasible or sustainable PIPT compared to other approaches.
This is not the first systematic review to summarize evidence on PIPT. We advance prior work by describing characteristics of the psychological approaches informing PIPT and include novel methods such as ACT and internet-based psychological programs. Our primary aim was to describe recent approaches and offer clinical implications and possible future directions. We did not meta-analyze outcome data from our included studies and are unable to confirm efficacy of specific PIPT approaches. Despite our structured and comprehensive search strategy, we cannot confirm that we have identified all studies since 2011 meeting our eligibility criteria.
Our review summarized findings from recent randomized trials that have examined the efficacy of PIPT compared to standard physical therapy approaches in patients with musculoskeletal pain. Consistent with prior reviews, graded activity is not superior to other forms of physical activity or exercise. A few studies on cognitive-behavioral-based physical therapy demonstrated short-term efficacy, when compared to a program of standardized exercise. There is a need to further examine approaches integrating alternative strategies including acceptance-based therapies (ie, ACT or mindfulness) or internet-based cognitive-behavioral programs within physical therapy. Although PIPT remains a promising care model, more convincing evidence is needed to support widespread adoption, especially in light of extensive training demands and implementation challenges.
The authors have no conflicts of interest to declare.
During manuscript development, R.A. Coronado was supported by a Vanderbilt Faculty Research Scholars Award.
Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article.
Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Web site ( www.painrpts.com ).
Otto D. Payton, Clinical Reasoning Process in Physical Therapy, Physical Therapy , Volume 65, Issue 6, 1 June 1985, Pages 924–928, https://doi.org/10.1093/ptj/65.6.924
The purpose of this descriptive study was to analyze physical therapists' clinical problem solving and compare the results with physicians' clinical problem solving. Ten skilled physical therapy clinicians were observed as they performed an initial interview with a patient. Their performance was audiotaped and later analyzed. The therapists defined their problem lists and developed treatment plans early in the interview, as they gathered data. This clinical problem-solving sequence is comparable to a method reported in the literature that is used by physicians. This model of clinical problem solving based on actual performance of clinicians can be used to train physical therapy students and, perhaps, to refine clinical evaluation skills.
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Vendrely, Ann PT, EdD, OCS
Ann Vendrely is university professor of physical therapy in the Department of Physical Therapy at Governors State University, 1 University Parkway, University Park, IL 60466 ( [email protected] ).
This study was approved by the Human Subjects Review Board of Governors State University and the Institutional Review Board of Loyola University Chicago. It was completed in partial fulfillment of the requirements for the degree of Doctor of Education at Loyola University Chicago.
Received July 28, 2003, and accepted November 15, 2004.
The purpose of this study was to determine if critical-thinking skills changed as a result of completing a 27-month, traditional physical therapist (PT) education curriculum at the postbaccalaureate level.
Forty-two students in graduating classes between 1998 and 2001 who completed the 27-month, master's degree PT professional education program agreed to participate. Subjects were 69% women and 31% men, with a mean age at admission to the program of 26.52 years and a range of 22-38 years.
The California Critical Thinking Skills Test (CCTST), a standardized examination consisting of 34 items in a multiple-choice format that is content neutral and designed for adults, was administered during the first week in the PT education program and again during the last week of the program. The number of correct responses formed the composite score on the test and on each of the three subscales. Each item on the test was categorized into one of three subscales defined as “analysis,” “inference,” and “evaluation.” A paired t test investigated the differences between pretest and posttest scores on the CCTST composite score and three subscale scores.
The mean score for the pretest CCTST cumulative of 19.32 was compared to the mean posttest of 20.61. T test results of the pretest and posttest CCTST showed no significant differences at the 0.05 level between the cumulative or sub-scale scores.
Critical-thinking abilities of PT professional students as measured by the CCTST did not change as a result of participation in a master's degree PT education program. Use of a different instrument or larger sample may provide further information about the critical-thinking skills of PT students. Development of critical-thinking skills appears to be an important goal of professional physical therapist education programs; however, meaningful measurement of changes in critical-thinking skills during the educational process remains difficult.
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Critical thinking skills and learning styles in entry-level doctor of physical therapy students</strong>', 'brudvig tracy j. pt dpt phd; mattson, d. j. pt, dpt, edd; guarino, a. j. phd', 'journal of physical therapy education', '2016', '30', '4' , 'p 3-10');" onmouseout="javascript:tooltip_mouseout()" class="ejp-uc__article-title-link"> critical thinking skills and learning styles in entry-level doctor of physical..., critical thinking skills in health care professional students: a systematic review</strong>', 'brudvig tracy j. pt dpt phd ocs; dirkes, angelique pt, dpt, ms; dutta, priyanka pt, ms; rane, kalpita pt, ms', 'journal of physical therapy education', 'fall 2013', '27', '3' , 'p 12-25');" onmouseout="javascript:tooltip_mouseout()" class="ejp-uc__article-title-link"> critical thinking skills in health care professional students: a systematic..., international service-learning and other international volunteer service in physical therapist education programs in the united states and canada: an exploratory study</strong>', 'pechak celia pt phd mph; thompson, mary pt, phd, gcs', 'journal of physical therapy education', 'spring 2009', '23', '1' , 'p 71-79');" onmouseout="javascript:tooltip_mouseout()" class="ejp-uc__article-title-link"> international service-learning and other international volunteer service in..., generic inabilities and the use of a decision-making rubric for addressing deficits in professional behavior</strong>', 'wolff-burke melissa pt edd atc; ingram, debbie pt, edd; lewis, kathy pt, jd; odom, corrie pt, dpt, atc; shoaf, lisa donegan pt, phd', 'journal of physical therapy education', 'winter 2007', '21', '3' , 'p 13-22');" onmouseout="javascript:tooltip_mouseout()" class="ejp-uc__article-title-link"> generic inabilities and the use of a decision-making rubric for addressing..., history of accreditation in physical therapy education</strong>', 'nieland virginia m pt ms; harris, mary jane pt, ms', 'journal of physical therapy education', 'winter 2003', '17', '3' , 'p 52-61');" onmouseout="javascript:tooltip_mouseout()" class="ejp-uc__article-title-link"> history of accreditation in physical therapy education.
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The authors developed an instrument called the “Rehabilitation Problem-Solving Form” (RPS-Form), which allows health care professionals analyze patient problems, to focus on specific targets, and to relate the salient disabilities to relevant and modifiable variables.
Clinical reasoning is a core skill needed for solving clinical problems and establishing rapport with patients. It allows healthcare providers, including physiotherapists, to integrate the patient's needs and experiences with their reasoning and decision-making in practice.
Problem-solving therapy is a brief intervention that provides people with the tools they need to identify and solve problems that arise from big and small life stressors. It aims to improve your overall quality of life and reduce the negative impact of psychological and physical illness.
Introduction. Clinical Reasoning is the process by which a therapist interacts with a patient, collecting information, generating and testing hypotheses, and determining optimal diagnosis and treatment based on the information obtained.
The clinical reasoning strategies of interaction, procedure, teaching, collaboration, prediction, and ethics represent foci of clinical decision making or action in areas of patient management that may be oriented in either paradigm at particular times within a clinical encounter.
Cognitive-behavioral-based physical therapy included a structured 12 session program (Back on Track) that stimulated patients to gain insight on pain mechanisms, behavior and beliefs, coping styles, goal setting, and self-management strategies. Graded activity and exposure were also included.
The authors in this issue provide us with options for moving through some of physical therapy education's more difficult problems.
The purpose of this descriptive study was to analyze physical therapists' clinical problem solving and compare the results with physicians' clinical problem solving. Ten skilled physical therapy clinicians were observed as they performed an initial interview with a patient.
The authors developed an instrument called the "Rehabilitation Problem-Solving Form" (RPS-Form), which allows health care professionals analyze patient problems, to focus on specific targets,...
The list includes CT as a separate item and several additional items that are often considered to be components of CT, such as problem solving, commitment to learning, use of constructive feedback, and responsibility. 5. Researchers in physical therapist education have had mixed results when measuring changes in CT among PT students.